(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamide

Name	S-10-Monohydroxy-Dihydro-Carbamazepin
Synonyms	(S)-LICARBAZEPINE-D4 Eslicarbazepine (BIA 2-194) S-10-Monohydroxy-Dihydro-Carbamazepin S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN (S)-10-Monohydroxydihydrocarbamazepine (10S)-10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE (10S)-10,11-Dihydro-10-hydroxy Carbamazepine Licarbazepine Impurity 2(Licarbazepine S-Isomer) (S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamide (10S)-10-hydroxy-10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carboxamide 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)- S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,S-MHD
CAS	104746-04-5
InChI	InChI=1/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1

Molecular Formula	C15H14N2O2
Molar Mass	254.28
Density	1.336
Melting Point	188-190°C
Boling Point	431.3±55.0 °C(Predicted)
Flash Point	214.628°C
Solubility	Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to Pale Yellow
pKa	13.75±0.20(Predicted)
Storage Condition	-20°C Freezer
Refractive Index	1.677
In vivo study	Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.

biological activity

Eslicarbazepine (BIA 2-194) is an oral anticonvulsant reagent that can be used for auxiliary research of local epilepsy.

Last Update：2024-04-09 20:45:29

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